PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32800810-0 2020 Amisulpride alleviates chronic mild stress-induced cognitive deficits: Role of prefrontal cortex microglia and Wnt/beta-catenin pathway. Amisulpride 0-11 catenin beta 1 Rattus norvegicus 115-127 32800810-4 2020 Hitherto, the direct effects of amisulpride on Wnt/beta-catenin signaling and microglial activity have not been thoroughly studied. Amisulpride 32-43 catenin beta 1 Rattus norvegicus 51-63 32800810-5 2020 This study aimed at investigating the effects of chronic amisulpride treatment on Wnt/beta-catenin signaling and pro-inflammatory microglial activation and its role in alleviation of depressive-like behavior and cognitive deficits elicited by unpredictable chronic mild stress (UCMS). Amisulpride 57-68 catenin beta 1 Rattus norvegicus 86-98 32800810-9 2020 Amisulpride improved UCMS-induced behavioral/cognitive deficits, ameliorated Wnt/beta-catenin signaling dysregulation and pro-inflammatory microglial activation. Amisulpride 0-11 catenin beta 1 Rattus norvegicus 81-93 32800810-10 2020 This work highlights the antidepressant and pro-cognitive effects of amisulpride in UCMS-exposed rats that could be mediated by modulation of Wnt/beta-catenin pathway activity and amelioration of pro-inflammatory microglial activation in the prefrontal cortex. Amisulpride 69-80 catenin beta 1 Rattus norvegicus 146-158