PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32771556-7 2020 Our results demonstrated that 3beta-hydroxycholest-5-en-7-one exerted an anti-inflammatory effect via miR-98-5p, which negatively regulated the expression of its target gene TNFAIP3. 7-ketocholesterol 30-61 tumor necrosis factor, alpha-induced protein 3 Mus musculus 174-181 32771556-8 2020 The results indicate that miR-98-5p interference and 3beta-hydroxycholest-5-en-7-one treatment significantly upregulated the low TNFAIP3 expression induced by LPS stimulation, thereby inhibiting TRAF6, RIP, NF-kappaB, IL-1beta, and TNF-alpha secretion. 7-ketocholesterol 53-84 tumor necrosis factor, alpha-induced protein 3 Mus musculus 129-136 32771556-9 2020 SIGNIFICANCE: 3beta-Hydroxycholest-5-en-7-one alleviates inflammation by downregulating miR-98-5p and upregulating TNFAIP3, thereby blocking NF-kappaB pathway activation. 7-ketocholesterol 14-45 tumor necrosis factor, alpha-induced protein 3 Mus musculus 115-122