PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32765665-0 2020 Ginsenoside Rg1 protects against Sca-1+ HSC/HPC cell aging by regulating the SIRT1-FOXO3 and SIRT3-SOD2 signaling pathways in a gamma-ray irradiation-induced aging mice model. ginsenoside Rg1 0-15 lymphocyte antigen 6 complex, locus A Mus musculus 33-38 32765665-11 2020 However, Rg1 significantly attenuated the senescence of Sca-1+ HSC/HPCs in the gamma-ray irradiation aging mice model. ginsenoside Rg1 9-12 lymphocyte antigen 6 complex, locus A Mus musculus 56-61 32765665-14 2020 The percentage of Sca-1+ HSC/HPCs arrested at the G1 phase in the Rg1 group was significantly decreased compared with that in the gamma-ray irradiation group (P<0.05). ginsenoside Rg1 66-69 lymphocyte antigen 6 complex, locus A Mus musculus 18-23 32765665-15 2020 In conclusion, the present study indicates that Rg1 exerts anti-aging effects via the regulation of SIRT1-FOXO3 and SIRT3-SOD2 signaling pathways, and triggering the progression of Sca-1+ HSC/HPCs from the G1 phase to the S phase in gamma-ray irradiation-induced aging mice. ginsenoside Rg1 48-51 lymphocyte antigen 6 complex, locus A Mus musculus 181-186