PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32649885-2 2020 To accommodate high ROS levels, tumor cells modify sulfur-based metabolism, NADPH generation, and the activity of antioxidant transcription factors. Reactive Oxygen Species 20-23 2,4-dienoyl-CoA reductase 1 Homo sapiens 76-81 32649885-3 2020 During initiation, genetic changes enable cell survival under high ROS levels by activating antioxidant transcription factors or increasing NADPH via the pentose phosphate pathway (PPP). Reactive Oxygen Species 67-70 2,4-dienoyl-CoA reductase 1 Homo sapiens 140-145