PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3262700-5 1988 When added 2 h or more before poly(I).poly(C), both forms of IL1 had a strong inhibitory effect on IFN-beta synthesis, as determined by antiviral assay of the IFN-beta protein or by quantitation of IFN-beta mRNA levels in Northern blot analysis. Poly C 38-45 interleukin 1 alpha Homo sapiens 61-64 3262700-6 1988 However, when IL1 was added simultaneously with poly(I).poly(C), or 2 h after poly(I).poly(C), IFN-beta synthesis was increased. Poly C 56-63 interleukin 1 alpha Homo sapiens 14-17 3262700-6 1988 However, when IL1 was added simultaneously with poly(I).poly(C), or 2 h after poly(I).poly(C), IFN-beta synthesis was increased. Poly C 56-62 interleukin 1 alpha Homo sapiens 14-17 3262700-7 1988 The inhibitory action of IL1 on poly(I).poly(C)-induced IFN-beta synthesis was abolished in the presence of cycloheximide, suggesting that it is mediated indirectly by an IL1-induced product in the FS-4 cells. Poly C 40-47 interleukin 1 alpha Homo sapiens 25-28 3262700-7 1988 The inhibitory action of IL1 on poly(I).poly(C)-induced IFN-beta synthesis was abolished in the presence of cycloheximide, suggesting that it is mediated indirectly by an IL1-induced product in the FS-4 cells. Poly C 40-47 interleukin 1 alpha Homo sapiens 171-174