PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32582992-7 2020 Significant changes in the E2F1/Cdc25a/Cdk2 pathway in the RB cells were detected by RNA-seq following carboplatin or lobaplatin intervention. Carboplatin 103-114 E2F transcription factor 1 L homeolog Xenopus laevis 27-31 32582992-8 2020 RT-qPCR, immunofluorescence and immunohistochemical analyses in vivo and in vitro demonstrated that the trends of drug-induced inhibition of tumor pathological changes may have been regulated through the E2F1/Cdc25a/Cdk2 pathway, and that lobaplatin was more effective than carboplatin in controlling tumors in vivo. Carboplatin 274-285 E2F transcription factor 1 L homeolog Xenopus laevis 204-208