PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32559056-3 2020 The effective dose resulted in pronounced functional responses on the transcript level based on RNA sequencing and quantitative polymerase chain reaction after reverse transcription (RT-qPCR), revealing desirable expression changes of genes related to neuroprotection, including Bdnf and Pax6 upregulation, extending the applicability of largazole to the treatment of brain cancer and neurodegenerative disorders. largazole 338-347 brain derived neurotrophic factor Mus musculus 279-283