PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32463794-2 2020 Metformin is capable of suppressing one of the molecular triggers of the proinflammatory and prothrombotic processes of urban PM air pollution, namely the mitochondrial ROS/Ca2+ release-activated Ca2+ channels (CRAC)/IL-6 cascade. Metformin 0-9 interleukin 6 Homo sapiens 217-221 32463794-3 2020 Given the linkage between mitochondrial functionality, ion channels, and inflamm-aging, the ability of metformin to target mitochondrial electron transport and prevent ROS/CRAC-mediated IL-6 release might illuminate new therapeutic avenues to quell the raging of the cytokine and thrombotic-like storms that are the leading causes of COVID-19 morbidity and mortality in older people. Metformin 103-112 interleukin 6 Homo sapiens 186-190