PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32458971-0 2020 Acetate promotes SNAI1 expression by ACSS2-mediated histone acetylation under glucose limitation in renal cell carcinoma cell. Acetates 0-7 acyl-CoA synthetase short chain family member 2 Homo sapiens 37-42 32458971-3 2020 In this study, we first measured the effect of acetate on zinc finger transcriptional repressor SNAI1 and acetyl-CoA synthetase 2 (ACSS2) under glucose limitation in renal cell carcinoma cell lines 786-O and ACHN. Acetates 47-54 acyl-CoA synthetase short chain family member 2 Homo sapiens 106-129 32458971-3 2020 In this study, we first measured the effect of acetate on zinc finger transcriptional repressor SNAI1 and acetyl-CoA synthetase 2 (ACSS2) under glucose limitation in renal cell carcinoma cell lines 786-O and ACHN. Acetates 47-54 acyl-CoA synthetase short chain family member 2 Homo sapiens 131-136 32458971-6 2020 The results showed that acetate increased the expressions of SNAI1 and ACSS2 under glucose limitation. Acetates 24-31 acyl-CoA synthetase short chain family member 2 Homo sapiens 71-76 32458971-7 2020 ACSS2 knockdown significantly decreased acetate-induced SNAI1 expression and cell migration, whereas overexpression of ACSS2 increased SNAI1 level and histone H3K27 acetylation (H3K27ac). Acetates 40-47 acyl-CoA synthetase short chain family member 2 Homo sapiens 0-5 32458971-9 2020 Our study identified a novel inducer, acetate, which can promote SNAI1 expression by ACSS2 mediated histone acetylation in partly. Acetates 38-45 acyl-CoA synthetase short chain family member 2 Homo sapiens 85-90