PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32457396-7 2020 Mechanistically, the Msi1-mTOR pathway drives keratinocyte-Paget-like cell conversion, and suppression of mTOR signaling with Rapamycin significantly rescued the Paget-like phenotype in Msi1-overexpressing transgenic mice. Sirolimus 126-135 mechanistic target of rapamycin kinase Mus musculus 106-110 32457396-7 2020 Mechanistically, the Msi1-mTOR pathway drives keratinocyte-Paget-like cell conversion, and suppression of mTOR signaling with Rapamycin significantly rescued the Paget-like phenotype in Msi1-overexpressing transgenic mice. Sirolimus 126-135 musashi RNA-binding protein 1 Mus musculus 186-190 32457396-8 2020 Topical Rapamycin treatment improved extramammary PD-associated symptoms in humans, suggesting mTOR inhibition as a novel therapeutic treatment in PD. Sirolimus 8-17 mechanistic target of rapamycin kinase Homo sapiens 95-99