PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32432943-2 2021 However, the current known SCAP inhibitors, such as oxysterols, induce endoplasmic reticulum (ER) stress and NR1H3/LXRalpha (nuclear receptor subfamily 1 group H member 3)-SREBF1/SREBP-1 c-mediated hepatic steatosis, which severely limited the clinical application of this inhibitor. Oxysterols 52-62 SREBF chaperone Mus musculus 27-31