PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32420164-1 2020 Background: Combining testosterone and phosphodiesterase 5 inhibitors (PDE5-Is) has become increasingly common in the treatment of men with erectile dysfunction (ED) and low testosterone levels, but combination therapy involving PDE5-Is and testosterone is highly debated, with strong reasons for and against argued by the various opinion leaders. Testosterone 22-34 phosphodiesterase 5A Homo sapiens 71-75 32420164-1 2020 Background: Combining testosterone and phosphodiesterase 5 inhibitors (PDE5-Is) has become increasingly common in the treatment of men with erectile dysfunction (ED) and low testosterone levels, but combination therapy involving PDE5-Is and testosterone is highly debated, with strong reasons for and against argued by the various opinion leaders. Testosterone 174-186 phosphodiesterase 5A Homo sapiens 71-75 32420164-1 2020 Background: Combining testosterone and phosphodiesterase 5 inhibitors (PDE5-Is) has become increasingly common in the treatment of men with erectile dysfunction (ED) and low testosterone levels, but combination therapy involving PDE5-Is and testosterone is highly debated, with strong reasons for and against argued by the various opinion leaders. Testosterone 174-186 phosphodiesterase 5A Homo sapiens 71-75 32420164-2 2020 PDE5-Is can be given prior to, alongside or after the commencement of any testosterone replacement therapy. Testosterone 74-86 phosphodiesterase 5A Homo sapiens 0-4 32420164-3 2020 Meanwhile, combination of PDE5-Is and testosterone is reported to better increase testosterone levels and thus improve International Index of Erectile Function (IIEF) score in hypogonadal men. Testosterone 82-94 phosphodiesterase 5A Homo sapiens 26-30 32420164-4 2020 The objective of this meta-analysis was to assess whether testosterone therapy (TTh) can possibly enhance the reaction to PDE5-Is in men with ED and hypogonadism. Testosterone 58-70 phosphodiesterase 5A Homo sapiens 122-126