PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32231130-0 2020 Burn-Induced Cardiac Mitochondrial Dysfunction via Interruption of the PDE5A-cGMP-PKG Pathway. Cyclic GMP 77-81 phosphodiesterase 5A Homo sapiens 71-76 32231130-3 2020 This study sought to understand whether burn-induced heart dysfunction is associated with cardiac mitochondrial dysfunction and interruption of the PDE5A-cGMP-PKG pathway. Cyclic GMP 154-158 phosphodiesterase 5A Homo sapiens 148-153 32231130-11 2020 Sildenafil, a inhibitor of the PDE5A-cGMP-PKG pathway, preserved the mitochondrial structure, respiratory chain efficiency and energy status in cardiac tissue. Cyclic GMP 37-41 phosphodiesterase 5A Homo sapiens 31-36 32231130-13 2020 In conclusion, cardiac mitochondrial damage contributes to burn-induced heart dysfunction via the PDE5A-cGMP-PKG pathway. Cyclic GMP 104-108 phosphodiesterase 5A Homo sapiens 98-103