PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32222530-0	2020	Metformin enhances the sensitivity of colorectal cancer cells to cisplatin through ROS-mediated PI3K/Akt signaling pathway.	Cisplatin	65-74	AKT serine/threonine kinase 1	Homo sapiens	101-104	
32222530-6	2020	Moreover, NAC could recover the downregulation of p-PI3K and p-Akt treated with combination of metformin and cisplatin, which subsequently activated the PI3K/Akt signaling pathway.	Cisplatin	109-118	AKT serine/threonine kinase 1	Homo sapiens	63-66	
32222530-7	2020	Taken together, our results demonstrated that metformin enhanced the sensitivity of CRC cells to cisplatin through ROS-mediated PI3K/Akt signaling pathway.	Cisplatin	97-106	AKT serine/threonine kinase 1	Homo sapiens	133-136