PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32186774-0 2020 miR-10a increases the cisplatin resistance of lung adenocarcinoma circulating tumor cells via targeting PIK3CA in the PI3K/Akt pathway. Cisplatin 22-31 AKT serine/threonine kinase 1 Homo sapiens 123-126 32186774-10 2020 Expression of phosphoinositide 3-kinase (PI3K) and protein kinase B (Akt) phosphorylation were also decreased in A549 and H1299 cells compared with CTCs after cisplatin treatment. Cisplatin 159-168 AKT serine/threonine kinase 1 Homo sapiens 69-72 32186774-13 2020 In conclusion, miR-10a suppressed the PI3K/Akt pathway to strengthen the resistance of CTCs to cisplatin via targeting PIK3CA, providing a new therapeutic target for lung cancer treatment. Cisplatin 95-104 AKT serine/threonine kinase 1 Homo sapiens 43-46