PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32156684-0 2020 Flavin-Containing Monooxygenase 1 (FMO1) Catalyzes the Production of Taurine from Hypotaurine. hypotaurine 82-93 flavin containing dimethylaniline monoxygenase 1 Homo sapiens 0-33 32156684-0 2020 Flavin-Containing Monooxygenase 1 (FMO1) Catalyzes the Production of Taurine from Hypotaurine. hypotaurine 82-93 flavin containing dimethylaniline monoxygenase 1 Homo sapiens 35-39 32156684-6 2020 Here we show, both in vivo and in vitro, that the enzyme that oxygenates hypotaurine to produce taurine is flavin-containing monooxygenase 1 (FMO1). hypotaurine 73-84 flavin containing dimethylaniline monoxygenase 1 Homo sapiens 107-140 32156684-6 2020 Here we show, both in vivo and in vitro, that the enzyme that oxygenates hypotaurine to produce taurine is flavin-containing monooxygenase 1 (FMO1). hypotaurine 73-84 flavin containing dimethylaniline monoxygenase 1 Homo sapiens 142-146 32156684-7 2020 Metabolite analysis of the urine of Fmo1-null mice by 1H NMR spectroscopy revealed a build-up of hypotaurine and a deficit of taurine in comparison with the concentrations of these compounds in the urine of wild-type mice. hypotaurine 97-108 flavin containing monooxygenase 1 Mus musculus 36-40 32156684-8 2020 In vitro assays confirmed that human FMO1 catalyzes the conversion of hypotaurine to taurine utilizing either NADPH or NADH as co-factor. hypotaurine 70-81 flavin containing dimethylaniline monoxygenase 1 Homo sapiens 37-41 32156684-10 2020 The identification that the endogenous molecule hypotaurine is a substrate for the FMO1-catalyzed production of taurine resolves a long-standing mystery. hypotaurine 48-59 flavin containing dimethylaniline monoxygenase 1 Homo sapiens 83-87 32156684-13 2020 Here we show, both in vivo and in vitro, that flavin-containing monooxygenase 1 (FMO1) catalyzes the oxygenation of hypotaurine to produce taurine. hypotaurine 116-127 flavin containing dimethylaniline monoxygenase 1 Homo sapiens 46-79 32156684-13 2020 Here we show, both in vivo and in vitro, that flavin-containing monooxygenase 1 (FMO1) catalyzes the oxygenation of hypotaurine to produce taurine. hypotaurine 116-127 flavin containing dimethylaniline monoxygenase 1 Homo sapiens 81-85