PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32152270-4 2020 A critical enzyme for TOP1cc resolution is the tyrosyl-DNA phosphodiesterase (TDP1), which hydrolyses the bond that links a tyrosine in the active site of TOP1 to a 3" phosphate group on a single-stranded (ss)DNA break. Tyrosine 124-132 tyrosyl-DNA phosphodiesterase 1 Homo sapiens 78-82