PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32108308-4	2021	Although nitrocatechol COMT inhibitors have been used in the treatment of Parkinson"s disease, efforts have been made to discover non-nitrocatechol inhibitors.	nitrocatechol	9-22	catechol-O-methyltransferase	Homo sapiens	23-27	
32108308-5	2021	In the present study, the 3-hydroxypyridin-4-one scaffold was selected for the design and synthesis of non-nitrocatechol COMT inhibitors since the COMT inhibitory potential of this class has been illustrated.	nitrocatechol	107-120	catechol-O-methyltransferase	Homo sapiens	121-125	
32108308-7	2021	Although these compounds are not highly potent inhibitors, they may act as leads for the development of non-nitrocatechol COMT inhibitors.	nitrocatechol	108-121	catechol-O-methyltransferase	Homo sapiens	122-126