PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32105160-12	2020	RESULTS: We measured higher proliferation in ER+ breast cancer cells treated with BPA or its replacement, BPS, accompanied by an ERalpha-dependent decrease in genomic DNA hydroxymethylation.	bisphenol A	82-85	estrogen receptor 1	Homo sapiens	129-136	
32105160-14	2020	On the other hand, we observed that TET2 was negatively regulated by the activation of ERalpha (dimerized and phosphorylated), which was also induced by BPA/BPS binding.	bisphenol A	153-156	estrogen receptor 1	Homo sapiens	87-94	
32105160-16	2020	CONCLUSIONS: We identified a new feedback circuit of ERalpha activation-DNMT-TET2-DNA hydroxymethylation in ER+ breast cancer cells and uncovered a pivotal role of TET2-mediated DNA hydroxymethylation in modulating BPA/BPS-stimulated proliferation.	bisphenol A	215-218	estrogen receptor 1	Homo sapiens	53-60