PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32048771-0 2020 Phase Ib Study of Crizotinib Plus Pembrolizumab in Patients with Previously Untreated Advanced Non-Small Cell Lung Cancer with ALK Translocation. crizotinib 18-28 ALK receptor tyrosine kinase Homo sapiens 127-130 32048771-1 2020 LESSONS LEARNED: This study evaluating first-line crizotinib plus pembrolizumab in patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) was terminated early because increased availability of second-generation ALK inhibitors resulted in difficulty identifying and accruing eligible patients. crizotinib 50-60 ALK receptor tyrosine kinase Homo sapiens 97-123 32048771-1 2020 LESSONS LEARNED: This study evaluating first-line crizotinib plus pembrolizumab in patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) was terminated early because increased availability of second-generation ALK inhibitors resulted in difficulty identifying and accruing eligible patients. crizotinib 50-60 ALK receptor tyrosine kinase Homo sapiens 125-128 32048771-5 2020 BACKGROUND: Previous research suggests single-agent crizotinib is efficacious for the treatment of anaplastic lymphoma kinase (ALK)-rearranged advanced non-small cell lung cancer (NSCLC). crizotinib 52-62 ALK receptor tyrosine kinase Homo sapiens 99-125 32048771-5 2020 BACKGROUND: Previous research suggests single-agent crizotinib is efficacious for the treatment of anaplastic lymphoma kinase (ALK)-rearranged advanced non-small cell lung cancer (NSCLC). crizotinib 52-62 ALK receptor tyrosine kinase Homo sapiens 127-130 32048771-6 2020 METHODS: This study evaluated the safety and preliminary antitumor activity of crizotinib plus pembrolizumab as first-line therapy in patients with ALK-rearranged NSCLC. crizotinib 79-89 ALK receptor tyrosine kinase Homo sapiens 148-151