PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31994352-4 2020 Structural analysis demonstrated the variant was located within the N-terminal domain of RyR2, likely leading to a gain-of-function effect facilitating enhanced calcium ion release. Calcium 161-168 ryanodine receptor 2 Homo sapiens 89-93