PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31941840-3 2020 Both TAC and SIR impaired insulin secretion in fasted and/or stimulated conditions. Sirolimus 13-16 insulin Homo sapiens 26-33 31941840-4 2020 Treatment with TAC or SIR increased amyloid deposition and islet macrophages, disrupted insulin granule formation, and induced broad transcriptional dysregulation related to peptide processing, ion/calcium flux, and the extracellular matrix; however, it did not affect regulation of beta cell mass. Sirolimus 22-25 insulin Homo sapiens 88-95