PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31926269-9 2020 2) Val200 is a critical determinant for exhibiting the strict 17beta-HSD activity of the enzyme, because the Val200Leu mutation resulted in both significant impairment of the 17beta-HSD activity and emergence of 3beta-HSD activity towards 5alpha-androstanes including 11KDHT. androstane 239-257 hydroxysteroid 17-beta dehydrogenase 1 Homo sapiens 62-72 31926269-9 2020 2) Val200 is a critical determinant for exhibiting the strict 17beta-HSD activity of the enzyme, because the Val200Leu mutation resulted in both significant impairment of the 17beta-HSD activity and emergence of 3beta-HSD activity towards 5alpha-androstanes including 11KDHT. androstane 239-257 hydroxysteroid 17-beta dehydrogenase 1 Homo sapiens 175-185