PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31904486-0 2020 All-trans retinoic acid exerts selective anti-FLT3-ITD acute myeloid leukemia efficacy through downregulating Chk1 kinase. Tretinoin 0-23 fms related receptor tyrosine kinase 3 Homo sapiens 46-50 31904486-2 2020 In this work, we report that ATRA causes fatal mitotic catastrophe in FLT3-ITD AML cells by degrading Chk1 kinase, and therefore preventing DNA damage repair. Tretinoin 29-33 fms related receptor tyrosine kinase 3 Homo sapiens 70-74