PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31829469-7 2020 Pretreatment of HL-7702 cells with OPN promotes hyperactivation of JNK and subsequent decrease of tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1), resulting in impaired insulin signaling, which can be reversed by inhibiting ER stress. Tyrosine 98-106 insulin receptor substrate 1 Mus musculus 126-154 31829469-7 2020 Pretreatment of HL-7702 cells with OPN promotes hyperactivation of JNK and subsequent decrease of tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1), resulting in impaired insulin signaling, which can be reversed by inhibiting ER stress. Tyrosine 98-106 insulin receptor substrate 1 Mus musculus 156-161