PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31816863-6 2019 RESULTS: Celecoxib reduced cell growth and induced apoptosis through AKT blockade, cleavage of poly (ADP-ribose) polymerase-1 (PARP-1), and proteasomal degradation of the anti-apoptotic protein Mcl-1. celecoxib 9-18 AKT serine/threonine kinase 1 Homo sapiens 69-72 31816863-6 2019 RESULTS: Celecoxib reduced cell growth and induced apoptosis through AKT blockade, cleavage of poly (ADP-ribose) polymerase-1 (PARP-1), and proteasomal degradation of the anti-apoptotic protein Mcl-1. celecoxib 9-18 poly(ADP-ribose) polymerase 1 Homo sapiens 95-125 31816863-6 2019 RESULTS: Celecoxib reduced cell growth and induced apoptosis through AKT blockade, cleavage of poly (ADP-ribose) polymerase-1 (PARP-1), and proteasomal degradation of the anti-apoptotic protein Mcl-1. celecoxib 9-18 poly(ADP-ribose) polymerase 1 Homo sapiens 127-133 31816863-6 2019 RESULTS: Celecoxib reduced cell growth and induced apoptosis through AKT blockade, cleavage of poly (ADP-ribose) polymerase-1 (PARP-1), and proteasomal degradation of the anti-apoptotic protein Mcl-1. celecoxib 9-18 MCL1 apoptosis regulator, BCL2 family member Homo sapiens 194-199 31816863-8 2019 Celecoxib reduced the invasive phenotype of CRPC cells by modulating NF-kappaB activity and reduced tumor growth in mice xenografts when administered in association with the anti-EGFR receptor antibody cetuximab. celecoxib 0-9 epidermal growth factor receptor Mus musculus 179-183