PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31786468-6 2020 Moreover, puerarin inhibited the phosphorylation of p38 and ERK mitogen-activated protein kinases (MAPKs) and signal transducer and activator of transcription 3 (STAT3), thereby protecting the retinal cells from apoptosis by suppressing cytochrome c release, caspase activation, and poly (ADP-ribose) polymerase cleavage in vivo. puerarin 10-18 signal transducer and activator of transcription 3 Mus musculus 110-160 31786468-6 2020 Moreover, puerarin inhibited the phosphorylation of p38 and ERK mitogen-activated protein kinases (MAPKs) and signal transducer and activator of transcription 3 (STAT3), thereby protecting the retinal cells from apoptosis by suppressing cytochrome c release, caspase activation, and poly (ADP-ribose) polymerase cleavage in vivo. puerarin 10-18 signal transducer and activator of transcription 3 Mus musculus 162-167 31786468-8 2020 The experimental data verify the protective role of puerarin in the treatment of retinal injury caused by iron overload; its possible mechanisms might be associated with regulation of iron-handling proteins, enhancement of the antioxidant capacity, and the inhibition of MAPK and STAT3 activation and the apoptotic pathways under iron overload conditions. puerarin 52-60 signal transducer and activator of transcription 3 Mus musculus 280-285