PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31785814-5 2020 Interestingly, the combination treatment of VPA and anti-PD-L1 antibody activated IRF1/IRF8 transcriptional axis in MDSCs leading to blockade of their immunosuppressive function by downregulating the expression of IL-10, IL-6, and ARG1 while re-activating CD8+ T-cells for the production of TNFalpha to further enhance anti-tumor immunity. Valproic Acid 44-47 interleukin 6 Homo sapiens 221-225