PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31683916-0	2019	Identifying Metabolic Perturbations and Toxic Effects of Rac-Metalaxyl and Metalaxyl-M in Mice Using Integrative NMR and UPLC-MS/MS Based Metabolomics.	metalaxyl	61-70	thymoma viral proto-oncogene 1	Mus musculus	57-60	
31683916-1	2019	Although metabolic perturbations are sensitive indicators for low-dose toxic effects, the metabolic mechanisms affected by rac-metalaxyl and metalaxyl-M in mammals from a metabolic profiling perspective remain unclear.	metalaxyl	127-136	thymoma viral proto-oncogene 1	Mus musculus	123-126	
31683916-2	2019	In this study, the metabolic perturbations and toxic effects of rac-metalaxyl and metalaxyl-M in mice were carefully investigated using integrative nuclear magnetic resonance (NMR) and ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) based metabolomics.	metalaxyl	68-77	thymoma viral proto-oncogene 1	Mus musculus	64-67	
31683916-3	2019	Histopathology, NMR-based untargeted urine profile, multivariate pattern recognition, metabolite identification, pathway analysis, UPLC-MS/MS based targeted serum amino acids, and tryptophan pathway analysis were determined after rac-metalaxyl and metalaxyl-M exposure, individually.	metalaxyl	234-243	thymoma viral proto-oncogene 1	Mus musculus	230-233	
31683916-5	2019	The metabolic perturbations induced by rac-metalaxyl and metalaxyl-M were directly separated using partial least-squares discriminant analysis (PLS-DA).	metalaxyl	43-52	thymoma viral proto-oncogene 1	Mus musculus	39-42	
31683916-8	2019	Serum amino acids and tryptophan pathway metabolite changes induced by rac-metalaxyl and metalaxyl-M were also different even at the same exposure level.	metalaxyl	75-84	thymoma viral proto-oncogene 1	Mus musculus	71-74	
31683916-9	2019	Such results may provide specific insight into the metabolic perturbations and toxic effects of rac-metalaxyl and metalaxyl-M, and contribute to providing available data for health risk assessments of rac-metalaxyl and metalaxyl-M at a metabolomics level.	metalaxyl	100-109	thymoma viral proto-oncogene 1	Mus musculus	96-99