PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31675556-0 2019 Curcumin functions as a MEK inhibitor to induce a synthetic lethal effect on KRAS mutant colorectal cancer cells receiving targeted drug regorafenib. Curcumin 0-8 mitogen-activated protein kinase kinase 7 Homo sapiens 24-27 31675556-6 2019 Mechanistically, curcumin behaved like MEK-specific inhibitor (U0126) to enhance regorafenib-induced growth inhibition, apoptosis and autophagy in HCT 116 cells. Curcumin 17-25 mitogen-activated protein kinase kinase 7 Homo sapiens 39-42