PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31664305-0 2019 Upregulation of miR-129-5p increases the sensitivity to Taxol through inhibiting HMGB1-mediated cell autophagy in breast cancer MCF-7 cells. Paclitaxel 56-61 microRNA 1295a Homo sapiens 16-26 31664305-0 2019 Upregulation of miR-129-5p increases the sensitivity to Taxol through inhibiting HMGB1-mediated cell autophagy in breast cancer MCF-7 cells. Paclitaxel 56-61 high mobility group box 1 Homo sapiens 81-86 31664305-4 2019 In this study, we aimed to explore the role of miR-129-5p in regulating the sensitivity of breast cancer cells to Taxol. Paclitaxel 114-119 microRNA 1295a Homo sapiens 47-56 31664305-8 2019 Furthermore, miR-129-5p overexpression increased the sensitivity of MCF-7 cells to Taxol. Paclitaxel 83-88 microRNA 1295a Homo sapiens 13-23 31664305-10 2019 We found that interference of HMGB1 enhanced the chemosensitivity of Taxol by inhibiting autophagy and inducing apoptosis in MCF-7 cells. Paclitaxel 69-74 high mobility group box 1 Homo sapiens 30-35 31664305-11 2019 Taken together, our findings suggested that miR-129-5p increased the chemosensitivity of MCF-7 cells to Taxol through suppressing autophagy and enhancing apoptosis by inhibiting HMGB1. Paclitaxel 104-109 microRNA 1295a Homo sapiens 44-54 31664305-11 2019 Taken together, our findings suggested that miR-129-5p increased the chemosensitivity of MCF-7 cells to Taxol through suppressing autophagy and enhancing apoptosis by inhibiting HMGB1. Paclitaxel 104-109 high mobility group box 1 Homo sapiens 178-183 31664305-12 2019 Using miR-129-5p/HMGB1/autophagy-based therapeutic strategies may be a potential treatment for overcoming Taxol resistance in breast cancer. Paclitaxel 106-111 microRNA 1295a Homo sapiens 6-16 31664305-12 2019 Using miR-129-5p/HMGB1/autophagy-based therapeutic strategies may be a potential treatment for overcoming Taxol resistance in breast cancer. Paclitaxel 106-111 high mobility group box 1 Homo sapiens 17-22