PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31659118-2	2019	For example, during amino acid limitations, ATF4 in the amino acid response induces expression of asparagine synthetase (ASNS), which provides for asparagine biosynthesis.	Asparagine	98-108	asparagine synthetase (glutamine-hydrolyzing)	Homo sapiens	121-125	
31659118-6	2019	Here we show that DNA hypermethylation at the ASNS promoter prevents its transcriptional expression following asparagine depletion.	Asparagine	110-120	asparagine synthetase (glutamine-hydrolyzing)	Homo sapiens	46-50	
31659118-8	2019	We conclude that chromatin accessibility is critical for ATF4 activity at the ASNS promoter, which can switch ALL cells from an ATF4-dependent adaptive response to ATF4-independent apoptosis during asparagine depletion.	Asparagine	198-208	asparagine synthetase (glutamine-hydrolyzing)	Homo sapiens	78-82