PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31650467-5 2020 The regulation of calcium on the expression level of hTERT and the possible underlying mechanism via CaSR were explored in gastric cancer cell lines MKN45 and SGC-7901. Calcium 18-25 telomerase reverse transcriptase Homo sapiens 53-58 31650467-7 2020 Calcium induced hTERT expression at the transcriptional level in a CaSR-dependent manner followed by an increase in telomerase activity, as either a CaSR shRNA or the CaSR antagonist NPS2143 abolished the calcium-mediated regulation of hTERT and telomerase activity. Calcium 0-7 telomerase reverse transcriptase Homo sapiens 16-21 31650467-7 2020 Calcium induced hTERT expression at the transcriptional level in a CaSR-dependent manner followed by an increase in telomerase activity, as either a CaSR shRNA or the CaSR antagonist NPS2143 abolished the calcium-mediated regulation of hTERT and telomerase activity. Calcium 0-7 telomerase reverse transcriptase Homo sapiens 236-241 31650467-7 2020 Calcium induced hTERT expression at the transcriptional level in a CaSR-dependent manner followed by an increase in telomerase activity, as either a CaSR shRNA or the CaSR antagonist NPS2143 abolished the calcium-mediated regulation of hTERT and telomerase activity. Calcium 205-212 telomerase reverse transcriptase Homo sapiens 16-21 31650467-7 2020 Calcium induced hTERT expression at the transcriptional level in a CaSR-dependent manner followed by an increase in telomerase activity, as either a CaSR shRNA or the CaSR antagonist NPS2143 abolished the calcium-mediated regulation of hTERT and telomerase activity. Calcium 205-212 telomerase reverse transcriptase Homo sapiens 236-241 31650467-8 2020 Further studies showed that CaSR-mediated cytosolic calcium rise followed by Akt activation was involved in the regulation of hTERT by extracellular calcium. Calcium 52-59 telomerase reverse transcriptase Homo sapiens 126-131 31650467-8 2020 Further studies showed that CaSR-mediated cytosolic calcium rise followed by Akt activation was involved in the regulation of hTERT by extracellular calcium. Calcium 149-156 telomerase reverse transcriptase Homo sapiens 126-131