PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31628042-3 2020 Here, we show that PTPS, which is highly expressed in early-stage colorectal cancer, is phosphorylated at Thr 58 by AMPK under hypoxia; this phosphorylation promotes PTPS binding to LTBP1 and subsequently drives iNOS-mediated LTBP1 S-nitrosylation through proximal-coupling BH4 production within the PTPS/iNOS/LTBP1 complex. peptide T amide 106-109 6-pyruvoyltetrahydropterin synthase Homo sapiens 19-23