PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31597092-0 2019 The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing. Fructose 47-55 APOBEC1 complementation factor Mus musculus 24-28 31597092-3 2019 Among these transcripts are isoforms for the dominant and high-affinity fructose-metabolizing ketohexokinase C and glycerol kinase, two key metabolic enzymes that are linked to hepatic gluconeogenesis and found to be markedly reduced upon hepatic ablation of A1cf. Fructose 72-80 APOBEC1 complementation factor Mus musculus 259-263 31597092-4 2019 Consequently, mice lacking A1CF exhibit improved glucose tolerance and are protected from fructose-induced hyperglycemia, hepatic steatosis, and development of obesity. Fructose 90-98 APOBEC1 complementation factor Mus musculus 27-31 31597092-5 2019 Our results identify a previously unreported function of A1CF as a regulator of alternative splicing of a subset of genes influencing hepatic glucose production through fructose and glycerol metabolism. Fructose 169-177 APOBEC1 complementation factor Mus musculus 57-61