PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31524237-7 2019 Compared with the control group, high glucose and bupivacaine significantly increased ATF4, CHOP and caspase-12 expression, increased apoptosis, and decreased p-IRE1, TRAF2, LC3-II/LC3-I and Beclin1 expression. Bupivacaine 50-61 beclin 1 Homo sapiens 191-198 31524237-8 2019 Promoting autophagy with RAPA partly reversed the high glucose and bupivacaine-induced changes in p-PERK, CHOP, TRAF2, Beclin1, caspase-12 and apoptosis, while inhibiting autophagy with 3-MA further enhanced the changes in ATF4, CHOP, p-IRE1, TRAF2 and apoptosis. Bupivacaine 67-78 beclin 1 Homo sapiens 119-126