PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31507377-10 2019 These data suggest that secretin acts on GnRH neurons via secretin receptors whose activation triggers the cAMP/PKA/nNOS signaling pathway resulting in nitric oxide release and in the presynaptic terminals this retrograde NO machinery regulates the GABAergic input to GnRH neurons. Cyclic AMP 107-111 nitric oxide synthase 1, neuronal Mus musculus 116-120