PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31491956-2	2019	ROS are known to activate the epidermal growth factor receptor (EGFR), which causes the activation of the Ras/mitogen-activated protein kinases (MAPKs) pathway.	Reactive Oxygen Species	0-3	epidermal growth factor receptor	Homo sapiens	30-62	
31491956-2	2019	ROS are known to activate the epidermal growth factor receptor (EGFR), which causes the activation of the Ras/mitogen-activated protein kinases (MAPKs) pathway.	Reactive Oxygen Species	0-3	epidermal growth factor receptor	Homo sapiens	64-68	
31491956-7	2019	Lycopene reduced the level of intracellular and mitochondrial ROS and decreased the activation of the ROS-mediated EGFR/Ras/extracellular signal-regulated kinase (ERK) and p38 MAPK pathways, thus leading to attenuation of the DNA-binding activity of NF-kappaB p50/p50 and the level of COX-2 gene expression.	Reactive Oxygen Species	102-105	epidermal growth factor receptor	Homo sapiens	115-119	
31491956-8	2019	These results show that lycopene-induced apoptosis and inhibition of proliferation occur via inhibition of ROS-activated EGFR/Ras/ERK and p38 MAPK pathways and NF-kappaB-mediated COX-2 gene expression in AGS cells.	Reactive Oxygen Species	107-110	epidermal growth factor receptor	Homo sapiens	121-125