PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31455656-0 2019 CD157 Confers Host Resistance to Mycobacterium tuberculosis via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production. Reactive Oxygen Species 91-114 bone marrow stromal cell antigen 1 Homo sapiens 0-5 31455656-0 2019 CD157 Confers Host Resistance to Mycobacterium tuberculosis via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production. Reactive Oxygen Species 91-114 bone marrow stromal cell antigen 1 Homo sapiens 69-74 31455656-4 2019 In vitro experiments show that the bactericidal ability was compromised in Cd157 knockout (KO) macrophages, which was due to impaired M. tuberculosis-induced reactive oxygen species (ROS) production. Reactive Oxygen Species 158-181 bone marrow stromal cell antigen 1 Homo sapiens 75-80 31455656-4 2019 In vitro experiments show that the bactericidal ability was compromised in Cd157 knockout (KO) macrophages, which was due to impaired M. tuberculosis-induced reactive oxygen species (ROS) production. Reactive Oxygen Species 183-186 bone marrow stromal cell antigen 1 Homo sapiens 75-80 31455656-5 2019 We further reveal that CD157 interacts with TLR2 and PKCzeta and facilitates M. tuberculosis-induced ROS production in Cd157 KO macrophages, which resulted in enhanced M. tuberculosis killing. Reactive Oxygen Species 101-104 bone marrow stromal cell antigen 1 Homo sapiens 23-28 31455656-5 2019 We further reveal that CD157 interacts with TLR2 and PKCzeta and facilitates M. tuberculosis-induced ROS production in Cd157 KO macrophages, which resulted in enhanced M. tuberculosis killing. Reactive Oxygen Species 101-104 bone marrow stromal cell antigen 1 Homo sapiens 119-124 31455656-10 2019 In conclusion, we have identified a novel protective immune function of CD157 during M. tuberculosis infection via TLR2-dependent ROS production. Reactive Oxygen Species 130-133 bone marrow stromal cell antigen 1 Homo sapiens 72-77