PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31434198-1 2019 Linagliptin is a representative of dipeptidyl peptidase 4 (DPP-4) inhibitors which are registered and used effectively in a treatment of diabetes mellitus type 2. Linagliptin 0-11 dipeptidylpeptidase 4 Rattus norvegicus 35-57 31434198-1 2019 Linagliptin is a representative of dipeptidyl peptidase 4 (DPP-4) inhibitors which are registered and used effectively in a treatment of diabetes mellitus type 2. Linagliptin 0-11 dipeptidylpeptidase 4 Rattus norvegicus 59-64 31434198-4 2019 Linagliptin"s administration leads to a decrease in the concentration of proinflammatory factors such as: TNF-alpha, IL-6 and increases the number of anti-inflammatory patrolling monocytes CX3CR1bright. Linagliptin 0-11 tumor necrosis factor Rattus norvegicus 106-115 31434198-4 2019 Linagliptin"s administration leads to a decrease in the concentration of proinflammatory factors such as: TNF-alpha, IL-6 and increases the number of anti-inflammatory patrolling monocytes CX3CR1bright. Linagliptin 0-11 interleukin 6 Rattus norvegicus 117-121 31434198-4 2019 Linagliptin"s administration leads to a decrease in the concentration of proinflammatory factors such as: TNF-alpha, IL-6 and increases the number of anti-inflammatory patrolling monocytes CX3CR1bright. Linagliptin 0-11 C-X3-C motif chemokine receptor 1 Rattus norvegicus 189-195 31434198-6 2019 Linagliptin improved vascular functions by increasing production of nitric oxide (NO) and limiting concentration of apolipoprotein B. Linagliptin 0-11 apolipoprotein B Rattus norvegicus 116-132 31434198-10 2019 Linagliptin prevented abnormal proliferation and migration of rat brain microvascular endothelial cells in a state of hypoperfusion via SIRT1/HIF-1alpha/VEGF pathway. Linagliptin 0-11 sirtuin 1 Rattus norvegicus 136-141 31434198-10 2019 Linagliptin prevented abnormal proliferation and migration of rat brain microvascular endothelial cells in a state of hypoperfusion via SIRT1/HIF-1alpha/VEGF pathway. Linagliptin 0-11 hypoxia inducible factor 1 subunit alpha Rattus norvegicus 142-152 31434198-10 2019 Linagliptin prevented abnormal proliferation and migration of rat brain microvascular endothelial cells in a state of hypoperfusion via SIRT1/HIF-1alpha/VEGF pathway. Linagliptin 0-11 vascular endothelial growth factor A Rattus norvegicus 153-157