PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31374317-0	2019	Bisphenol A affects estradiol metabolism by targeting CYP1A1 and CYP19A1 in human placental JEG-3 cells.	Estradiol	20-29	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	54-60	
31374317-5	2019	Additionally, by lentiviral transduction, we determined that estradiol level of JEG-3 cells over-expressing CYP1A1 gene was notably decreased and the decrease was of 84.9% compared to the control.	Estradiol	61-70	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	108-114	
31374317-8	2019	In summary, our research clearly showed that BPA alters JEG-3 estradiol synthesis and catabolism due to its action on CYP1A1 and CYP19A1 protein levels and may interfere with the normal process of placenta formation and embryonic development during early pregnancy.	Estradiol	62-71	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	118-124