PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31369842-0 2019 Inhibition of neointima hyperplasia by the combined therapy of linagliptin and metformin via AMPK/Nox4 signaling in diabetic rats. Metformin 79-88 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 93-97 31369842-11 2019 Linagliptin and metformin were synergistical to target AMPK/Nox4 signal pathway in VSMCs incubated with HG and in the cardia artery of diabetic rats, which was superior to the monotherapy. Metformin 16-25 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 55-59 31369842-12 2019 CONCLUSIONS: We demonstrated that the potential protection of the combined use of linagliptin and metformin on VSMC remodeling through AMPK/Nox4 signal pathway, resulting in the improvement of neointima hyperplasia in diabetic rats. Metformin 98-107 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 135-139