PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31364164-12 2019 These findings establish XMU-MP-3 as a novel inhibitor of BTK, which could serve as both a tool compound and a lead for further drug development in BTK relevant B-cell malignancies, especially those with the acquired ibrutinib-resistant C481S mutation. ibrutinib 217-226 Bruton agammaglobulinemia tyrosine kinase Mus musculus 58-61