PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31363380-0	2019	Trimetazidine inhibits cardiac fibrosis by reducing reactive oxygen species and downregulating connective tissue growth factor in streptozotocin-induced diabetic rats.	Trimetazidine	0-13	cellular communication network factor 2	Rattus norvegicus	95-126	
31363380-3	2019	The present study aimed to determine the modulatory effect of TMZ on reactive oxygen species (ROS) and connective tissue growth factor (CTGF) expression and to evaluate the potential of TMZ to improve diastolic function in streptozotocin (STZ)-induced diabetic rats.	Trimetazidine	62-65	cellular communication network factor 2	Rattus norvegicus	103-134	
31363380-4	2019	After treating STZ-induced diabetic rats with TMZ for 16 weeks, a decrease in malondialdehyde levels, cardiac collagen volume fraction, left ventricular (LV) end-diastolic pressure and protein expression of collagen-I (Col I), Col III and CTGF compared with those in diabetic control rats was observed.	Trimetazidine	46-49	cellular communication network factor 2	Rattus norvegicus	239-243	
31363380-5	2019	In vitro, TMZ inhibited Col I, Col III and CTGF protein expression in cardiac fibroblasts treated with high glucose and decreased intracellular ROS generation and hydroxyproline content in the cell culture medium of cardiac fibroblasts.	Trimetazidine	10-13	cellular communication network factor 2	Rattus norvegicus	43-47