PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31331356-3	2019	Here the authors intended to identify the role of HMGB1 in Hank"s balanced salt solution (HBSS)-induced autophagy, explore NIS protein degradation through a autophagy-lysosome pathway in thyroid cancer cells and elucidate the possible molecular mechanisms.	hbss	90-94	high mobility group box 1	Homo sapiens	50-55	
31331356-12	2019	RESULTS: HMGB1 was a critical regulator of autophagy-mediated NIS degradation in HBSS-treated FTC-133/TPC-1 cells.	hbss	81-85	high mobility group box 1	Homo sapiens	9-14	
31331356-14	2019	HMGB1-knockdown dramatically suppressed autophagy, NIS degradation and boosted iodide uptake in HBSS-treated cells.	hbss	96-100	high mobility group box 1	Homo sapiens	0-5	
31331356-15	2019	Moreover, HBSS enhanced ROS-sustained autophagy and promoted the cytosolic translocation of HMGB1.	hbss	10-14	high mobility group box 1	Homo sapiens	92-97