PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31299216-16 2019 CONCLUSIONS: Cardiac function and cardiac fibrosis were significantly exacerbated in mice fed diets supplemented with either choline or TMAO, probably through accelerating the transformation of fibroblasts into myofibroblasts, indicating activation of TGF-betaRI/Smad2 pathway. Choline 125-132 SMAD family member 2 Mus musculus 263-268