PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31278195-4	2019	Mice lacking a receptor on their erythrocytes called ADORA2B, which increases O2 delivery, and patients with CKD were studied to assess the role of ADORA2B-mediated O2 delivery in CKD.	Oxygen	78-80	adenosine A2b receptor	Mus musculus	53-60	
31278195-4	2019	Mice lacking a receptor on their erythrocytes called ADORA2B, which increases O2 delivery, and patients with CKD were studied to assess the role of ADORA2B-mediated O2 delivery in CKD.	Oxygen	165-167	adenosine A2b receptor	Homo sapiens	148-155	
31278195-5	2019	RESULTS: Untargeted metabolomics showed increased production of 2,3-biphosphoglycerate (2,3-BPG), an erythrocyte-specific metabolite promoting O2 delivery, in mice given Ang II to induce CKD.	2,3-biphosphoglycerate	64-86	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	170-176	
31278195-5	2019	RESULTS: Untargeted metabolomics showed increased production of 2,3-biphosphoglycerate (2,3-BPG), an erythrocyte-specific metabolite promoting O2 delivery, in mice given Ang II to induce CKD.	2,3-Diphosphoglycerate	88-95	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	170-176	
31278195-6	2019	Genetic studies in mice revealed that erythrocyte ADORA2B signaling leads to AMPK-stimulated activation of BPG mutase, promoting 2,3-BPG production and O2 delivery to counteract kidney hypoxia, tissue damage, and disease progression in Ang II-induced CKD.	2,3-Diphosphoglycerate	129-136	adenosine A2b receptor	Mus musculus	50-57	
31278195-6	2019	Genetic studies in mice revealed that erythrocyte ADORA2B signaling leads to AMPK-stimulated activation of BPG mutase, promoting 2,3-BPG production and O2 delivery to counteract kidney hypoxia, tissue damage, and disease progression in Ang II-induced CKD.	Oxygen	152-154	adenosine A2b receptor	Mus musculus	50-57	
31278195-10	2019	CONCLUSIONS: Mouse and human evidence reveals that ADORA2B-AMPK signaling cascade-induced 2,3-BPG production promotes O2 delivery by erythrocytes to counteract kidney hypoxia and progression of CKD.	2,3-Diphosphoglycerate	90-97	adenosine A2b receptor	Homo sapiens	51-58	
31278195-10	2019	CONCLUSIONS: Mouse and human evidence reveals that ADORA2B-AMPK signaling cascade-induced 2,3-BPG production promotes O2 delivery by erythrocytes to counteract kidney hypoxia and progression of CKD.	Oxygen	118-120	adenosine A2b receptor	Homo sapiens	51-58