PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31235732-3 2019 In this study, by assessing miRNAs simultaneously targeting a set of DDR genes that exhibited response to platinum, we found that miR-211 inhibited most of those genes, and proposed that miR-211 might affect the sensitivity of ovarian cancer cells to platinum by targeting multiple DDR genes and thereby determine the prognosis of ovarian cancer. Platinum 106-114 microRNA 211 Homo sapiens 130-137 31235732-3 2019 In this study, by assessing miRNAs simultaneously targeting a set of DDR genes that exhibited response to platinum, we found that miR-211 inhibited most of those genes, and proposed that miR-211 might affect the sensitivity of ovarian cancer cells to platinum by targeting multiple DDR genes and thereby determine the prognosis of ovarian cancer. Platinum 106-114 microRNA 211 Homo sapiens 187-194 31235732-3 2019 In this study, by assessing miRNAs simultaneously targeting a set of DDR genes that exhibited response to platinum, we found that miR-211 inhibited most of those genes, and proposed that miR-211 might affect the sensitivity of ovarian cancer cells to platinum by targeting multiple DDR genes and thereby determine the prognosis of ovarian cancer. Platinum 251-259 microRNA 211 Homo sapiens 130-137 31235732-3 2019 In this study, by assessing miRNAs simultaneously targeting a set of DDR genes that exhibited response to platinum, we found that miR-211 inhibited most of those genes, and proposed that miR-211 might affect the sensitivity of ovarian cancer cells to platinum by targeting multiple DDR genes and thereby determine the prognosis of ovarian cancer. Platinum 251-259 microRNA 211 Homo sapiens 187-194 31235732-7 2019 In contrast, TDP1 suppressed DNA damage and platinum chemosensitivity. Platinum 44-52 tyrosyl-DNA phosphodiesterase 1 Homo sapiens 13-17 31235732-9 2019 Conclusively, we demonstrated that miR-211 improves the prognosis of ovarian cancer patients by enhancing the chemosensitivity of cancer cells to platinum via inhibiting DDR gene expression, which provides an essential basis to identify novel treatment targets to block DDR effectively and improve chemosensitivity in ovarian cancer. Platinum 146-154 microRNA 211 Homo sapiens 35-42