PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31233189-0 2019 Activation of AKT/AP1/FoxM1 signaling confers sorafenib resistance to liver cancer cells. Sorafenib 46-55 AKT serine/threonine kinase 1 Homo sapiens 14-17 31233189-10 2019 Inhibition of AKT using BEZ-235 markedly suppressed the upregulation of c-jun and FoxM1, and increased the sensitivity of drug-resistant cells to sorafenib in vitro and in vivo. Sorafenib 146-155 AKT serine/threonine kinase 1 Homo sapiens 14-17 31233189-11 2019 The data indicated that the activation of the AKT/AP1/FoxM1 signaling axis is an important determinant of sorafenib tolerance. Sorafenib 106-115 AKT serine/threonine kinase 1 Homo sapiens 46-49