PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31213500-4 2019 METHODS: This was an investigator-initiated, phase I, dose escalation study of the MEK inhibitor binimetinib combined with pexidartinib, a potent inhibitor of CSF1R, KIT, and FLT3, in patients with advanced or metastatic GIST who progressed on imatinib. pexidartinib 123-135 fms related receptor tyrosine kinase 3 Homo sapiens 175-179